What does asbestos have to do with mesothelioma?
The only known cause of mesothelioma in the U.S. is previous exposure to asbestos fibers. Asbestos manufacturers knew the dangers of asbestos it is seventy years - but kept that information to themselves. The first warnings to workers exposed to asbestos in the mid-1960s, and were totally inadequate. Even today, workers are not always told they are working around asbestos and are at risk of asbestos disease.
What can you do with mesothelioma?
* Find updates and the latest.
* Find the best medical care.
* Screening for the diagnosis of mesothelioma.
* Stay in touch with your doctor.
* Please note that due to this issue of asbestos-injury.
* Remember that the resources available to you through community support groups and medical organizations of victims of asbestos, place of worship, and to his family and friends.
Mesothelioma Treatment:
Doctors specializing in the treatment of mesothelioma often adopt a multimodal approach: a patient treated with a combination of therapies. Because of the relatively low efficiency of one mode affect patient survival, the combination of multimodal promising treatments for a longer survival of patients with malignant mesothelioma.
In December 1999, the medical journal Chest published a clinical case presentation shows a fairly typical processing multi-modal. The patient was a 52-year old diagnosed with early stage I pleural mesothelioma. Doctors performed a pleurectomy (surgery) and then given doses of intrapleural chemotherapy. Then, an additional radiotherapy and chemotherapy deleted. Two years after surgery there was no evidence of tumor.
The author concludes that aggressive treatment for mesothelioma trimodal presented as an effective treatment option.
In recent years some progress in the treatment of mesothelioma have been mainly used in the combination of active ingredients and processing methods. .
The following analysis of treatments for mesothelioma is divided into different sections (surgery, photodynamic therapy, radiation, etc.) so that each component of a combination of treatments (multimodal treatment) may be better understood to be organized.
Treatment Options Mesothelioma - Surgery
There are two types of surgical treatment of pleural mesothelioma: pleural pneumonectomy Outer (EPP) and pleurectomy / decortication.
PSA is the removal of the pleura, diaphragm, pericardium, and entire lung involved in the tumor. Pleurectomy / decortication is the removal of the pleura, without all the lung.
What is the recommended treatment depends on many factors, including tumor stage. (The National Cancer Institute, a detailed description of the stages of mesothelioma a.) It is unclear whether the benefits far greater than EPP offers pleurectomy / decortication, which is whether it is significantly more effective than other surgical options .
A recent study followed 400 patients with mesothelioma from 1983 to 1998 had pleurectomy / decortication or extra-pleural pneumonectomy (EPP) or thoracotomy. The results show that it was a type of surgery more effective than others in extending survival. However, other factors seem to determine how long he survived. These factors include the nature of the stage, and tumor cells of the patient's sex and type of treatment (n) is given with the operation.
Surgery can relieve and sometimes more of the tumor can be removed. Surgery is often used in combination with other treatments (also known as multimodal therapy), but their value is limited when the tumor is close to vital organs.
Both EPP and pleurectomy / decortication are generally non-complex surgery, most surgeons have performed. reference centers required for these treatments. Many of these centers specialize in other forms of mesothelioma treatment, either alone or in combination (multimodal therapy). You should talk to your doctor recommendations.
mesothelioma treatment options - radiation therapy (radiotherapy)
This treatment involves the localized application of high doses of radiation (like X-rays) in malignant tumors. Normally, not a primary treatment is used in combination with other therapies such as surgical resection and chemotherapy. It is commonly used to reduce tumor size and symptomatic relief of symptoms such as pain and difficulty breathing.
Factors that may limit the application of this treatment, the tumor size and proximity to vital organs.
Options for treatment of mesothelioma - Photodynamic therapy
Photodynamic therapy (PDT) is a method of treatment is often used in combination with other treatments such as drugs or surgery. Paris uses light to kill cancer cells. Photodynamic therapy is still experimental for treatment of mesothelioma.
The first is that the patient is a photosensitizer that accumulates in cancer cells but not healthy cells. (A photosensitizer is a drug that cancer cells found sensitive (sensitive) in the light of certain wavelengths permits.) After the cells have been sensitized, fiber optic cables are placed on the body (most often by open chest surgery) in the light of the correct frequency in the tumor focus. This is the photosensitizer to a molecule of oxygen toxicity that kills the cells produce.
Mesothelioma Treatment - Gene therapy and immunotherapy
Immunotherapy
And biological therapy is known, is based on the theory that it is possible to mobilize the body's immune response to cancer cells is based. Another name often applied to this treatment, biological response modifiers (BRM).
Gene Therapy
This new treatment is currently in clinical trials. The use of an adenovirus to deliver "suicide gene" is inserted directly into the tumor. This gene normally causes the cells sensitive to a drug effect because glanciclovir. Treatment with the drug then kills the rapidly dividing cells - while leaving healthy cells unharmed - cancer cells.
In theory, this approach allows a treatment targeting the tumor, compared with treatments such as chemotherapy that kill healthy cells.Gene treatment for mesothelioma is studied at the University of Pennsylvania, with Dr. Steven Albelda as principal investigator. This treatment is not without risk, as evidenced by the death of Jesse Gelsinger at the University of Pennsylvania gene therapy participants. (Note that Mr. Gelsinger participated in the study of mesothelioma.)
Cytokines - Interferon (IFN) and interleukin (IL)
Cytokines are small proteins that are naturally in the human body. Similarly, hormones and have a particular impact on the behavior of other cells.
In 1976, Dr. Robert Gallo isolated (later director of the National Cancer Institute and is famous for his work on HIV), a protein molecule called cytokine interleukin-2 (IL2), which are capable of stimulating growth cells of immune system cells called T lymphocytes T. are sometimes called "killer cells" because the search for virus-infected cells and destroy them or malicious. With IL-2 for treatment of pleural mesothelioma is still experimental, but researchers hope that the injection of IL-2 intrapleural a significant immune response against tumors promoted.
Interferons are natural proteins of cytokines, but also to strengthen inhibit the growth of malignant cells and the immune system. Such as interleukins, are the promoters of the immune system is tested, if they contribute to increase the body's response to what is often a malignant tumor is very resistant, mesothelioma.
Options for treatment of mesothelioma - angiogenesis therapies
Cancer cells, like other cells in the human body, and its growth in a rich blood supply. You must perform a network of capillaries and large blood vessels, cells are surrounded. The medical term for the process of development of this network is to angiogenesis.
In fact, the fastest growing cancer are very effective in promoting angiogenesis. Produce angiogenesis promoters, a network of capillaries and blood vessels of the tumor. The tumor is fed by a growing source of oxygen-rich blood, which develops and spreads (or metastasis).
Angiogenesis is essential to understand the process, such as tumors grow and metastasize, medical researchers began studying how could stop, slow down or reduce angiogenesis. If they could do, it is estimated could deprive the tumor to death - or at least slow growth significantly. The National Cancer Institute has created an illustrated educational materials to better understand how angiogenesis.
A number of anti-angiogenic drugs that were developed as inhibitors of angiogenesis and angiogenesis inhibitors. decrease in animals with tumors that have caused the tumor or even disappear completely administered. Combrestatin endostatin, angiostatin, thrombospondin, and inhibitors of vascular endothelial growth factor (VEG) are among these drug candidates.
Some of these drugs have been tested in humans. One combrestatin, which destroys the lining of blood vessels around tumors. Another endostatin, acts by preventing the growth of new blood vessels in the tumor. Endostatin have some promising developments. Dana-Farber Cancer Institute at Harvard published an updated report on phase 1 of the inhibitor of angiogenesis and says he has virtually no toxicity even at high doses, while reducing tumors in two of 28 patients advanced cancer and slow the progression of the disease with four others for more than six months.
This area of cancer research is very promising for the treatment of malignant mesothelioma tumors, but it is very early and experimental stages.
Options for treatment of mesothelioma - unconventional treatments
A number of treatments of mesothelioma are outside the mainstream of established and experimental treatments. For example, lawyers, doctors are not qualified to value these non-conventional treatments or judge unproven. In our experience, most doctors condemn these treatments, and there is no clear evidence, not anecdotal success of any of these treatments. However, we believe you are entitled to all available information so that you explore all options with your doctor and make an informed decision about your choice.
1. Antineoplastons
Dr. Stanislaw Burzynski antineoplastons worked as a treatment for cancer since 1967. Antineoplastons are naturally occurring peptides, Dr. Burzynski claims can "reprogram" cancer cells such as cells, "normal" behavior again. Successful treatment antineoplastons was very controversial, however. The American Cancer Society reports that no reliable information on the possible advantages antineoplastons goals. Dr. Burzynski has also in 1995 for fraud and violation of the Federal Drug Administration accused. The Burzynski Research Institute conducts clinical trials antineoplastons.
2. Cancel (also called Entelev or Cantron)
An annulment is a chemical mixture that deprive cancer cells reach their capacity, energy. Developed by chemist James Sheridan, according to proponents, that people have tried to cancel the operation and animals successfully against cancer for over 30 years without serious side effects. However, say the advocates of repeal also recommended avoiding certain vitamins and cancels the effects of chemotherapy cancel. The National Cancer Institute found no evidence of a biological effect. The American Cancer Society urges against the use of methods of treatment should be discontinued.
3. Clinical Affairs
There are numerous clinics, usually located outside the United States, the use of innovative and successful claims to cure cancer. Most of these clinics are expensive, and none has been proven.
4. Augmentative immunotherapy (AIT) Center, Freeport, Grand Bahama Island
TAI treatment center is daily administration of a specially prepared serum is claimed to stimulate the immune system and vice versa, the process of carcinogenesis.
Lawrence Burton (a PhD instead of an MD) is to strengthen the treatment and the main defender. This practice is illegal in most U.S. and the FDA has banned imports in 1986. In 1985, the clinic was closed by the Bahamian government because of evidence of the spread of HIV, hepatitis B and bacterial products in the RAI. Reopened next year if IAT acquired HIV test kits, but since the products are not tested regularly by an independent laboratory, not the actual risk of biological contamination is known.
The benefits of immune therapy tested under load, although there are numerous reports of its effectiveness. In fact, no independent study on the IATs products detainees, despite direct attempts by the National Cancer Institute and the Office of Technology Assessment. The American Cancer Society recommends that the immuno-augmentative therapy. Plus the cost of highly processed, patients must pay for room and board.
5. American biological Mexico SA Medical Center in Tijuana, Mexico
Mesothelioma patients first treated in this clinic was the actor Steve McQueen. Since then, there have been few reports of successful treatment, but no conclusive evidence. The treatment consists of an "individualized" approach to the "metabolic therapy" consisting of nutrition, vitamins, exercise and other techniques. They claim that the "control" of cancer and many other diseases and not as a "cure". AB Clinical Mexico with the Research Institute attached Bradford.
6. Gerson Therapy: Center for Integrative Medicine at the Pacific International Hospital (Chips) and Meridian Hospital in Playas de Tijuana, Mexico
There are two clinics in Tijuana, Mexico, the treatment on offer based Gerson Therapy: The Center for Integrative Medicine at the Pacific International Hospital (Chips) and Meridian Hospital in Playas de Tijuana. The treatment was developed by Dr. Max Gerson in 1945, and his daughter, Charlotte Gerson Strauss, therapy continued since his death in 1959.
With food (fresh fruit juices, raw consumed continuously for 13 hours a day), enemas (including coffee enemas) and other therapies, the Gerson Therapy clinics claim to detoxify the body and restore its natural ability to fight against cancer.
According to the National Cancer Institute, Dr. Gerson, methods studied and there is no convincing evidence of the effectiveness of cancer was detected. No other independent study has shown that the Gerson therapy is effective against cancer. In 1989 the regime crude calf liver juice, and use of this juice has been associated with various infections caused by pollution. Coffee enemas have also been associated with serious side effects such as fluid and electrolyte abnormalities.
CHIPS Gerson therapy treatment methods of Dr. Josef Issels developed together. Call Gerson Issels combination therapy.
7. Greek cancer cure Alivizatos
Greek cancer cure was thirty years ago by a microbiologist Dr. Hariton Tzannis Alivizatos. His treatment consisted of a blood test, which are supposed to diagnose the situation and extent of cancer by injections of serum, which aims to stimulate the immune system and "resolve" to follow the tumor. Before his death in 1991, Dr. Alivizatos his license to practice medicine by the Greek government had repeatedly canceled due to the use of the practice of serum. Never responded to the National Cancer Institute and the American Cancer Society to request information about your treatment. He has never published its results or allow an independent review of their claims. If a physician Seattle a patient's serum was found that the combination of niacin (vitamin B) and water, his clinic was closed by the Greek government.
Today, some clinics claim to North America to offer the same treatment under the name and METBAL Cellbal sold. The FDA has banned the import of METBAL
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